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By about 25 days the cephalic and caudal closure of the neural tube, at the anterior neuropore and posterior neuropore, becomes complete and the neural plate is converted into the neural tube. The cephalic closure of the neural tube is marked by the lamina terminalis of the adult.
After closure of the neural tube, the expanded rostral portion of the neural tube will differentiate and subdivide into three vesicles representing the forebrain, midbrain and hindbrain.
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